Expertise on fate and exposure of organic contaminants in biological and environmental matrices, including expertise in sorption processes, bioaccumulation and kinetic modeling. High quality analytical measurements of concentrations of (mixtures of) organic chemicals in biological and environmental matrices, including drugs, industrial chemicals and environmental pollutants in body fluids, tissues, water, air, soil and sediments. . Examples of substances being measured: PAHs, PCBs, VOCs (BTEX), oil, petrochemical hydrocarbons, organochloride pollutants, C60 fullerene, and priority emerging contaminants. Analytical equipment: GC-MS/ECD/FID, HPLC-UV/FLD/ELSD, LC-MS/MS.
Development of methods to sample, extract, clean-up, fractionate, derivatise, and analyse chemicals with ‘cumbersome’ physicochemical properties, such as strongly hydrophobic, volatile and surfactant-like chemicals.
Determination of the bioavailable (freely dissolved) concentration of chemicals in biological and environmental samples. Determination of partition coefficients/binding affinities of chemicals to protein, membranes, fat, organisms (bioaccumulation), polymers, sediments, etc.
In situ and ex situ passive sampling and passive dosing method development, including solid phase (micro)extraction (SP(M)E). High quality non-vertebrate toxicity tests, including critical body residue (CBR) tests and acute toxicity tests.
- Jonker, M. T .O. (2016).
Determining octanol-water partition coefficients for extremely hydrophobic chemicals by combining 'slow stirring' and solid phase micro extraction.
Environ. Toxicol. Chem. 35(6), 1371-1377.
- Hawthorne, S. B., Jonker, M. T. O., Van der Heijden, S. A., Grabanski, C. B., Azzolina, N. A. & Miller, D. J. (2011).
Measuring picogram per liter concentrations of freely dissolved parent and alkyl PAHs (PAH-34), using passive sampling with polyoxymethylene.
Anal. Chem. 83(17), 6754-6761.
- Quinn, C. L., Van der Heijden, S. A., Wania, F. & Jonker, M. T. O. (2014).
Partitioning of polychlorinated biphenyls into human cells and adipose tissues: Evaluation of octanol, triolein, and liposomes as surrogates.
Environ. Sci. Technol. 48(10), 5920-5928.
- Muijs, B. & Jonker, M. T. O. (2012).
Does equilibrium passive sampling reflect actual in situ bioaccumulation of PAHs and petroleum hydrocarbon mixtures in aquatic worms?
Environ. Sci. Technol. 46(2), 937-944.